A Vibrio parahaemolyticus T3SS Effector Mediates Pathogenesis by Independently Enabling Intestinal Colonization and Inhibiting TAK1 Activation

Vibrio parahaemolyticus type III secretion system 2 (T3SS2) is essential for the organism’s virulence, but the effectors required for intestinal colonization and induction of diarrhea by this pathogen have not been identified. Here, we identify a type III secretion system (T3SS2)-secreted effector,...

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Bibliographic Details
Main Authors: Xiaohui Zhou, Benjamin E. Gewurz, Jennifer M. Ritchie, Kaoru Takasaki, Hannah Greenfeld, Elliott Kieff, Brigid M. Davis, Matthew K. Waldor
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713001630