Innate Immune Modulation Induced by EBV Lytic Infection Promotes Endothelial Cell Inflammation and Vascular Injury in Scleroderma

by Antonella Farina, Edoardo Rosato, Michael York, Benjamin E. Gewurz, Benjamin E. Gewurz, Benjamin E. Gewurz, Maria Trojanowska, Giuseppina Alessandra Farina
Published 2021-04-01

NF-κB and IRF7 Pathway Activation by Epstein-Barr Virus Latent Membrane Protein 1

by Benjamin E. Gewurz, Ina Ersing, Katharina Bernhardt
Published 2013-06-01

CRISPR–Cas9 Genetic Analysis of Virus–Host Interactions

by Makda Gebre, Jason L. Nomburg, Benjamin E. Gewurz
Published 2018-01-01

A Vibrio parahaemolyticus T3SS Effector Mediates Pathogenesis by Independently Enabling Intestinal Colonization and Inhibiting TAK1 Activation

by Xiaohui Zhou, Benjamin E. Gewurz, Jennifer M. Ritchie, Kaoru Takasaki, Hannah Greenfeld, Elliott Kieff, Brigid M. Davis, Matthew K. Waldor
Published 2013-05-01

Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival.

by Liang Wei Wang, Zhonghao Wang, Ina Ersing, Luis Nobre, Rui Guo, Sizun Jiang, Stephen Trudeau, Bo Zhao, Michael P Weekes, Benjamin E Gewurz
Published 2019-09-01

TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation.

by Hannah Greenfeld, Kaoru Takasaki, Michael J Walsh, Ina Ersing, Katharina Bernhardt, Yijie Ma, Bishi Fu, Camille W Ashbaugh, Jackson Cabo, Sarah B Mollo, Hufeng Zhou, Shitao Li, Benjamin E Gewurz
Published 2015-05-01

Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence.

by Alessio Iannetti, Adeline C Ledoux, Susan J Tudhope, Hélène Sellier, Bo Zhao, Sophia Mowla, Adam Moore, Holger Hummerich, Benjamin E Gewurz, Simon J Cockell, Parmjit S Jat, Elaine Willmore, Neil D Perkins
Published 2014-09-01

SARS-CoV-2 hijacks folate and one-carbon metabolism for viral replication

by Yuchen Zhang, Rui Guo, Sharon H. Kim, Hardik Shah, Shuting Zhang, Jin Hua Liang, Ying Fang, Matteo Gentili, Colin N. O’ Leary, Steven J. Elledge, Deborah T. Hung, Vamsi K. Mootha, Benjamin E. Gewurz
Published 2021-03-01

A Temporal Proteomic Map of Epstein-Barr Virus Lytic Replication in B Cells

by Ina Ersing, Luis Nobre, Liang Wei Wang, Lior Soday, Yijie Ma, Joao A. Paulo, Yohei Narita, Camille W. Ashbaugh, Chang Jiang, Nicholas E. Grayson, Elliott Kieff, Steven P. Gygi, Michael P. Weekes, Benjamin E. Gewurz
Published 2017-05-01

The NF-κB Genomic Landscape in Lymphoblastoid B Cells

by Bo Zhao, Luis A. Barrera, Ina Ersing, Bradford Willox, Stefanie C.S. Schmidt, Hannah Greenfeld, Hufeng Zhou, Sarah B. Mollo, Tommy T. Shi, Kaoru Takasaki, Sizun Jiang, Ellen Cahir-McFarland, Manolis Kellis, Martha L. Bulyk, Elliott Kieff, Benjamin E. Gewurz
Published 2014-09-01

CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation

by Chang Jiang, Stephen J. Trudeau, Taek-Chin Cheong, Rui Guo, Mingxiang Teng, Liang Wei Wang, Zhonghao Wang, Chiara Pighi, Carole Gautier-Courteille, Yijie Ma, Sizun Jiang, Chong Wang, Bo Zhao, Luc Paillard, John G. Doench, Roberto Chiarle, Benjamin E. Gewurz
Published 2019-07-01