Unveiling six potent and highly selective antileishmanial agents via the open source compound collection ‘Pathogen Box’ against antimony-sensitive and -resistant Leishmania braziliensis
Despite all efforts to provide new chemical entities to tackle leishmaniases, we are still dependent on a the limited drug arsenal, together with drawbacks like toxicity and drug-resistant parasites. Collaborative drug discovery emerged as an option to speed up the way to find alternative antileishm...
Main Authors: | Juliano A. Souza Silva, Luiza G. Tunes, Roney S. Coimbra, David B. Ascher, Douglas E.V. Pires, Rubens L. Monte-Neto |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332220312415 |
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