Unveiling six potent and highly selective antileishmanial agents via the open source compound collection ‘Pathogen Box’ against antimony-sensitive and -resistant Leishmania braziliensis

Despite all efforts to provide new chemical entities to tackle leishmaniases, we are still dependent on a the limited drug arsenal, together with drawbacks like toxicity and drug-resistant parasites. Collaborative drug discovery emerged as an option to speed up the way to find alternative antileishm...

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Bibliographic Details
Main Authors: Juliano A. Souza Silva, Luiza G. Tunes, Roney S. Coimbra, David B. Ascher, Douglas E.V. Pires, Rubens L. Monte-Neto
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
MMV
PKA
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220312415