Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.
Drosophila Lnk is the single ancestral orthologue of a highly conserved family of structurally-related intracellular adaptor proteins, the SH2B proteins. As adaptors, they lack catalytic activity but contain several protein-protein interaction domains, thus playing a critical role in signal transduc...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-03-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2841611?pdf=render |