Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria

Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria

Mercaptopyruvate sulfurtransferase (Mpst) and its homolog thiosulfate sulfurtransferase (Tst = rhodanese) detoxify cyanide to thiocyanate. Mpst is attracting attention as one of the four endogenous hydrogen sulfide (H<sub>2</sub>S)/reactive sulfur species (RSS)-producing enzymes, along w...

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Bibliographic Details
Main Authors:	Noriyuki Akahoshi, Tatsuro Minakawa, Masashi Miyashita, Uran Sugiyama, Chihiro Saito, Rintaro Takemoto, Akihiro Honda, Waka Kamichatani, Shotaro Kamata, Yasumi Anan, Isao Ishii
Format:	Article
Language:	English
Published:	MDPI AG 2020-01-01
Series:	International Journal of Molecular Sciences
Subjects:	crispr/cas9 cystathionine γ-lyase hydrogen sulfide mercaptolactate-cysteine disulfiduria mercaptopyruvate sulfurtransferase passive systemic anaphylaxis reactive sulfur species thiosulfate sulfurtransferase
Online Access:	https://www.mdpi.com/1422-0067/21/3/818

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