Preparation of co-crystals of human PPARα-LBD and ligand for high-resolution X-ray crystallography

by Shotaro Kamata, Takuji Oyama, Isao Ishii
Published 2021-03-01

Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice

by Kamila Borowczyk, Jacek Wróblewski, Joanna Suliburska, Noriyuki Akahoshi, Isao Ishii, Hieronim Jakubowski
Published 2018-01-01

Preeclampsia-Like Features and Partial Lactation Failure in Mice Lacking Cystathionine γ-Lyase—An Animal Model of Cystathioninuria

by Noriyuki Akahoshi, Hiroki Handa, Rintaro Takemoto, Shotaro Kamata, Masahide Yoshida, Tatsushi Onaka, Isao Ishii
Published 2019-07-01

The Gasotransmitter Hydrogen Sulfide (H₂S) Prevents Pathologic Calcification (PC) in Cartilage

by Sonia Nasi, Driss Ehirchiou, Jessica Bertrand, Mariela Castelblanco, James Mitchell, Isao Ishii, Alexander So, Nathalie Busso
Published 2021-09-01

Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis

by Ravinder R Gaddam, Stephen Chambers, Robin Fraser, Victoria C Cogger, David G Le Couteur, Isao Ishii, Madhav Bhatia
Published 2019-06-01

Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis.

by Ravinder Reddy Gaddam, Robin Fraser, Alireza Badiei, Stephen Chambers, Victoria C Cogger, David G Le Couteur, Isao Ishii, Madhav Bhatia
Published 2016-01-01

Correction: Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis.

by Ravinder Reddy Gaddam, Robin Fraser, Alireza Badiei, Stephen Chambers, Victoria C Cogger, David G Le Couteur, Isao Ishii, Madhav Bhatia
Published 2017-01-01

Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disu...

by Noriyuki Akahoshi, Tatsuro Minakawa, Masashi Miyashita, Uran Sugiyama, Chihiro Saito, Rintaro Takemoto, Akihiro Honda, Waka Kamichatani, Shotaro Kamata, Yasumi Anan, Isao Ishii
Published 2020-01-01

Hydrogen Sulfide Treatment Improves Post-Infarct Remodeling and Long-Term Cardiac Function in CSE Knockout and Wild-Type Mice

by Leigh J. Ellmers, Evelyn M. Templeton, Anna P. Pilbrow, Chris Frampton, Isao Ishii, Philip K. Moore, Madhav Bhatia, A. Mark Richards, Vicky A. Cameron
Published 2020-06-01

PPARα Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates

by Shotaro Kamata, Takuji Oyama, Kenta Saito, Akihiro Honda, Yume Yamamoto, Keisuke Suda, Ryo Ishikawa, Toshimasa Itoh, Yasuo Watanabe, Takahiro Shibata, Koji Uchida, Makoto Suematsu, Isao Ishii
Published 2020-11-01

Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2*

by Hitoshi Ikeda, Naoko Watanabe, Isao Ishii, Tatsuo Shimosawa, Yukio Kume, Tomoaki Tomiya, Yukiko Inoue, Takako Nishikawa, Natsuko Ohtomo, Yasushi Tanoue, Satoko Iitsuka, Ryoto Fujita, Masao Omata, Jerold Chun, Yutaka Yatomi
Published 2009-03-01