Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology

α-Synuclein (α-syn), a small protein that has the intrinsic propensity to aggregate, is implicated in several neurodegenerative diseases including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA), which are collectively known as synucleinopathies. Genetic,...

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Bibliographic Details
Main Authors:	Nishant N. Vaikath, Nour K. Majbour, Katerina E. Paleologou, Mustafa T. Ardah, Esther van Dam, Wilma D.J. van de Berg, Shelley L. Forrest, Laura Parkkinen, Wei-Ping Gai, Nobutaka Hattori, Masashi Takanashi, Seung-Jae Lee, David M.A. Mann, Yuzuru Imai, Glenda M. Halliday, Jia-Yi. Li, Omar M.A. El-Agnaf
Format:	Article
Language:	English
Published:	Elsevier 2015-07-01
Series:	Neurobiology of Disease
Subjects:	α-Synuclein Conformation-specific monoclonal antibodies Parkinson’s disease Dementia with Lewy bodies
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996115001564

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http://www.sciencedirect.com/science/article/pii/S0969996115001564

Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology

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