Inhibition of alpha-synuclein fibrillization by dopamine is mediated by interactions with five C-terminal residues and with E83 in the NAC region.

by Fernando E Herrera, Alessandra Chesi, Katerina E Paleologou, Adrian Schmid, Adriana Munoz, Michele Vendruscolo, Stefano Gustincich, Hilal A Lashuel, Paolo Carloni
Published 2008-01-01

Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts

by Mustafa T. Ardah, Simona S. Ghanem, Sara A. Abdulla, Guohua Lv, Mohamed M. Emara, Katerina E. Paleologou, Nishant N. Vaikath, Jia-Hong Lu, Min Li, Konstantinos Vekrellis, David Eliezer, Omar M. A. El-Agnaf
Published 2020-03-01

Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils

by Mustafa T. Ardah, Katerina E. Paleologou, Guohua Lv, Sindhu A. Menon, Salema B. Abul Khair, Jia-Hong Lu, Bared Safieh-Garabedian, Abdulmonem A. Al-Hayani, David Eliezer, Min Li, Omar M.A. El-Agnaf
Published 2015-02-01

Elevated Levels of Cerebrospinal Fluid α-Synuclein Oligomers in Healthy Asymptomatic LRRK2 Mutation Carriers

by Jan eAasly, Krisztina eJohansen, Gunnar eBrønstad, Bjørg eWarø, Nour eMajbour, Shiji eVarghese, Fatimah eAlzahmi, Katerina ePaleologou, Dena eAmer, Abdulmonem eAl-Hayani, Omar eEl-Agnaf
Published 2014-09-01

Structure Activity Relationship of Phenolic Acid inhibitors of α-Synuclein Fibril Formation and Toxicity

by Mustafa eArdah, Katerina ePaleologou, Guohua eLv, Salema eAbul Khair, Abdullah eAl Kendi, Saeed eMinhas, Taleb eAl-Tel, Abdulmonem eAl-Hayani, Mohammed eHaque, David eEliezer, Omar eEl-Agnaf, Omar eEl-Agnaf
Published 2014-08-01

Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology

by Nishant N. Vaikath, Nour K. Majbour, Katerina E. Paleologou, Mustafa T. Ardah, Esther van Dam, Wilma D.J. van de Berg, Shelley L. Forrest, Laura Parkkinen, Wei-Ping Gai, Nobutaka Hattori, Masashi Takanashi, Seung-Jae Lee, David M.A. Mann, Yuzuru Imai, Glenda M. Halliday, Jia-Yi. Li, Omar M.A. El-Agnaf
Published 2015-07-01