Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge.

Dogs represent the most important domestic reservoir of L. chagasi (syn. L. infantum). A vaccine against canine visceral leishmaniasis (CVL) would be an important tool for decreasing the anxiety related to possible L. chagasi infection and for controlling human visceral leishmaniasis (VL). Because t...

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Main Authors: Lucilene Aparecida Resende, Rodrigo Dian de Oliveira Aguiar-Soares, Henrique Gama-Ker, Bruno Mendes Roatt, Ludmila Zanandreis de Mendonça, Marina Luiza Rodrigues Alves, Denise da Silveira-Lemos, Rodrigo Corrêa-Oliveira, Olindo Assis Martins-Filho, Márcio Sobreira Silva Araújo, Ricardo Toshio Fujiwara, Nelder Figueiredo Gontijo, Alexandre Barbosa Reis, Rodolfo Cordeiro Giunchetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4996460?pdf=render