Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease

by Bruno Mendes Roatt, Bruno Mendes Roatt, Bruno Mendes Roatt, Rodrigo D.O. Aguiar-Soares, Rodrigo D.O. Aguiar-Soares, Wendel eCoura-Vital, Henrique G. Ker, Nádia das Dores Moreira, Juliana eVitoriano-Souza, Rodolfo Cordeiro Giunchetti, Rodolfo Cordeiro Giunchetti, Cláudia Martins Carneiro, Alexandre Barbosa Reis, Alexandre Barbosa Reis, Alexandre Barbosa Reis
Published 2014-06-01

Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis

by Mariana Costa Duarte, Daniela Pagliara Lage, Vívian Tamietti Martins, Miguel Angel Chávez-Fumagalli, Bruno Mendes Roatt, Daniel Menezes-Souza, Luiz Ricardo Goulart, Manuel Soto, Carlos Alberto Pereira Tavares, Eduardo Antonio Ferraz Coelho

Prevalence and factors associated with Leishmania infantum infection of dogs from an urban area of Brazil as identified by molecular methods.

by Wendel Coura-Vital, Marcos José Marques, Vanja Maria Veloso, Bruno Mendes Roatt, Rodrigo Dian de Oliveira Aguiar-Soares, Levi Eduardo Soares Reis, Samuel Leôncio Braga, Maria Helena Franco Morais, Alexandre Barbosa Reis, Mariângela Carneiro
Published 2011-08-01

Parasite burden in hamsters infected with two different strains of leishmania (Leishmania) infantum: "Leishman Donovan units" versus real-time PCR.

by Nádia das Dores Moreira, Juliana Vitoriano-Souza, Bruno Mendes Roatt, Paula Melo de Abreu Vieira, Henrique Gama Ker, Jamille Mirelle de Oliveira Cardoso, Rodolfo Cordeiro Giunchetti, Cláudia Martins Carneiro, Marta de Lana, Alexandre Barbosa Reis
Published 2012-01-01

Phase I and II Clinical Trial Comparing the LBSap, Leishmune^®, and Leish-Tec^® Vaccines against Canine Visceral Leishmaniasis

by Rodrigo Dian de Oliveira Aguiar-Soares, Bruno Mendes Roatt, Fernando Augusto Siqueira Mathias, Levi Eduardo Soares Reis, Jamille Mirelle de Oliveira Cardoso, Rory Cristiane Fortes de Brito, Henrique Gama Ker, Rodrigo Corrêa-Oliveira, Rodolfo Cordeiro Giunchetti, Alexandre Barbosa Reis
Published 2020-11-01

Performance of LBSap vaccine after intradermal challenge with L. infantum and saliva of Lu. longipalpis: immunogenicity and parasitological evaluation.

by Bruno Mendes Roatt, Rodrigo Dian de Oliveira Aguiar-Soares, Juliana Vitoriano-Souza, Wendel Coura-Vital, Samuel Leôncio Braga, Rodrigo Corrêa-Oliveira, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Marta de Lana, Nelder Figueiredo Gontijo, Marcos José Marques, Rodolfo Cordeiro Giunchetti, Alexandre Barbosa Reis
Published 2012-01-01

Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice

by Rory Cristiane Fortes De Brito, Jamille Mirelle de Oliveira Cardoso, Levi Eduardo Soares Reis, Fernando Augusto Siqueira Mathias, Rodrigo Dian de Oliveira Aguiar-Soares, Andréa Teixeira-Carvalho, Bruno Mendes Roatt, Rodrigo Corrêa-Oliveira, Jeronimo Conceição Ruiz, Daniela de Melo Resende, Alexandre Barbosa Reis
Published 2019-10-01

The TcI and TcII Trypanosoma cruzi experimental infections induce distinct immune responses and cardiac fibrosis in dogs

by Ana Luiza Cassin Duz, Paula Melo de Abreu Vieira, Bruno Mendes Roatt, Rodrigo Dian Oliveira Aguiar-Soares, Jamille Mirelle de Oliveira Cardoso, Flávia Carvalho Bitencourt de Oliveira, Levi Eduardo Soares Reis, Washington Luiz Tafuri, Vanja Maria Veloso, Alexandre Barbosa Reis, Cláudia Martins Carneiro
Published 2014-12-01

Clinical forms of canine visceral Leishmaniasis in naturally Leishmania infantum-infected dogs and related myelogram and hemogram changes.

by Roney de Carvalho Nicolato, Raquel Trópia de Abreu, Bruno Mendes Roatt, Rodrigo Dian de Oliveira Aguiar-Soares, Levi Eduardo Soares Reis, Maria das Graças Carvalho, Cláudia Martins Carneiro, Rodolfo Cordeiro Giunchetti, Leoneide Erica Maduro Bouillet, Denise Silveira Lemos, Wendel Coura-Vital, Alexandre Barbosa Reis
Published 2013-01-01

Evaluation of change in canine diagnosis protocol adopted by the visceral leishmaniasis control program in Brazil and a new proposal for diagnosis.

by Wendel Coura-Vital, Henrique Gama Ker, Bruno Mendes Roatt, Rodrigo Dian Oliveira Aguiar-Soares, Gleisiane Gomes de Almeida Leal, Nádia das Dores Moreira, Laser Antônio Machado Oliveira, Evandro Marques de Menezes Machado, Maria Helena Franco Morais, Rodrigo Corrêa-Oliveira, Mariângela Carneiro, Alexandre Barbosa Reis
Published 2014-01-01

Chimeric Vaccines Designed by Immunoinformatics-Activated Polyfunctional and Memory T Cells That Trigger Protection against Experimental Visceral Leishmaniasis

by Rory Cristiane Fortes De Brito, Jeronimo Conceição Ruiz, Jamille Mirelle de Oliveira Cardoso, Thais Lopes Valentim Di Paschoale Ostolin, Levi Eduardo Soares Reis, Fernando Augusto Siqueira Mathias, Rodrigo Dian de Oliveira Aguiar-Soares, Bruno Mendes Roatt, Rodrigo Corrêa-Oliveira, Daniela de Melo Resende, Alexandre Barbosa Reis
Published 2020-05-01

Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge.

by Lucilene Aparecida Resende, Rodrigo Dian de Oliveira Aguiar-Soares, Henrique Gama-Ker, Bruno Mendes Roatt, Ludmila Zanandreis de Mendonça, Marina Luiza Rodrigues Alves, Denise da Silveira-Lemos, Rodrigo Corrêa-Oliveira, Olindo Assis Martins-Filho, Márcio Sobreira Silva Araújo, Ricardo Toshio Fujiwara, Nelder Figueiredo Gontijo, Alexandre Barbosa Reis, Rodolfo Cordeiro Giunchetti
Published 2016-01-01

Selection strategy of phage-displayed immunogens based on an in vitro evaluation of the Th1 response of PBMCs and their potential use as a vaccine against Leishmania infantum infec...

by Fernanda Fonseca Ramos, Lourena Emanuele Costa, Daniel Silva Dias, Thaís Teodoro Oliveira Santos, Marcella Rezende Rodrigues, Daniela Pagliara Lage, Beatriz Cristina Silveira Salles, Vívian Tamietti Martins, Patrícia Aparecida Fernandes Ribeiro, Miguel Angel Chávez-Fumagalli, Ana Carolina Silva Dias, Patrícia Terra Alves, Érica Leandro Marciano Vieira, Bruno Mendes Roatt, Daniel Menezes-Souza, Mariana Costa Duarte, Antonio Lúcio Teixeira, Luiz Ricardo Goulart, Eduardo Antonio Ferraz Coelho
Published 2017-12-01