Role of Membrane Cholesterol Levels in Activation of Lyn upon Cell Detachment

Role of Membrane Cholesterol Levels in Activation of Lyn upon Cell Detachment

Cholesterol, a major component of the plasma membrane, determines the physicalproperties of biological membranes and plays a critical role in the assembly of membranemicrodomains. Enrichment or deprivation of membrane cholesterol affects the activities of manysignaling molecules at the plasma membra...

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Bibliographic Details
Main Authors: Takao Morinaga, Noritaka Yamaguchi, Yuji Nakayama, Masatoshi Tagawa, Naoto Yamaguchi
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:International Journal of Molecular Sciences
Subjects:
cholesterol
Src-family kinases
subcellular localization
membrane distribution
Lyn activation
cell–scaffold interactions
cell detachment
Online Access:http://www.mdpi.com/1422-0067/19/6/1811

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http://www.mdpi.com/1422-0067/19/6/1811

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