A Potential Therapeutic Strategy for Malignant Mesothelioma with Gene Medicine

by Yuji Tada, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
Published 2013-01-01

Role of Membrane Cholesterol Levels in Activation of Lyn upon Cell Detachment

by Takao Morinaga, Noritaka Yamaguchi, Yuji Nakayama, Masatoshi Tagawa, Naoto Yamaguchi
Published 2018-06-01

A Possible Anticancer Agent, Type III Interferon, Activates Cell Death Pathways and Produces Antitumor Effects

by Masatoshi Tagawa, Kiyoko Kawamura, Quanhai Li, Yuji Tada, Kenzo Hiroshima, Hideaki Shimada
Published 2011-01-01

Gene Expressions for Signal Transduction under Acidic Conditions

by Masatoshi Tagawa, Hiromi Saito, Xin Wang, Syunsuke Ikeda, Toshihiko Fukamachi, Hiroshi Kobayashi
Published 2013-03-01

Augmented expression of cardiac ankyrin repeat protein is induced by pemetrexed and a possible marker for the pemetrexed resistance in mesothelioma cells

by Yiyang Qin, Ikuo Sekine, Mengmeng Fan, Yuichi Takiguchi, Yuji Tada, Masato Shingyoji, Michiko Hanazono, Naoto Yamaguchi, Masatoshi Tagawa
Published 2017-12-01

An MDM2 inhibitor achieves synergistic cytotoxic effects with adenoviruses lacking E1B55kDa gene on mesothelioma with the wild-type p53 through augmenting NFI expression

by Thao Thi Thanh Nguyen, Masato Shingyoji, Michiko Hanazono, Boya Zhong, Takao Morinaga, Yuji Tada, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
Published 2021-07-01

Diffuse pleural thickening and thoracic contraction: An indistinguishable case from malignant pleural mesothelioma

by Yuji Tada, Masatoshi Tagawa, Toshikazu Yusa, Mari Yatomi, Iwao Shimomura, Toshio Suzuki, Yuichiro Takeshita, Tetsuo Sato, Hideaki Shimada, Kenzo Hiroshima
Published 2020-08-01

AMPK activation induced in pemetrexed‐treated cells is associated with development of drug resistance independently of target enzyme expression

by Yiyang Qin, Ikuo Sekine, Michiko Hanazono, Takao Morinaga, Mengmeng Fan, Yuichi Takiguchi, Yuji Tada, Masato Shingyoji, Naoto Yamaguchi, Masatoshi Tagawa
Published 2019-06-01

Metformin produces growth inhibitory effects in combination with nutlin-3a on malignant mesothelioma through a cross-talk between mTOR and p53 pathways

by Kengo Shimazu, Yuji Tada, Takao Morinaga, Masato Shingyoji, Ikuo Sekine, Hideaki Shimada, Kenzo Hiroshima, Takao Namiki, Koichiro Tatsumi, Masatoshi Tagawa
Published 2017-05-01

Zoledronic acid produces combinatory anti-tumor effects with cisplatin on mesothelioma by increasing p53 expression levels.

by Shinya Okamoto, Yuanyuan Jiang, Kiyoko Kawamura, Masato Shingyoji, Toshihiko Fukamachi, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Hiroshi Kobayashi, Masatoshi Tagawa
Published 2013-01-01

An image cytometric technique is a concise method to detect adenoviruses and host cell proteins and to monitor the infection and cellular responses induced

by Takao Morinaga, Thảo Thi Thanh Nguyễn, Boya Zhong, Michiko Hanazono, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
Published 2017-11-01

Fas Ligand DNA Enhances a Vaccination Effect by Coadministered DNA Encoding a Tumor Antigen through Augmenting Production of Antibody against the Tumor Antigen

by Boya Zhong, Guangyu Ma, Ayako Sato, Osamu Shimozato, Hongdan Liu, Quanhai Li, Masato Shingyoji, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
Published 2015-01-01

Cytotoxicity of replication-competent adenoviruses powered by an exogenous regulatory region is not linearly correlated with the viral infectivity/gene expression or with the E1A-a...

by Suguru Yamauchi, Boya Zhong, Kiyoko Kawamura, Shan Yang, Shuji Kubo, Masato Shingyoji, Ikuo Sekine, Yuji Tada, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
Published 2017-09-01

Interferon-β produces synergistic combinatory anti-tumor effects with cisplatin or pemetrexed on mesothelioma cells.

by Quanhai Li, Kiyoko Kawamura, Shan Yang, Shinya Okamoto, Hiroshi Kobayashi, Yuji Tada, Ikuo Sekine, Yuichi Takiguchi, Masato Shingyouji, Koichiro Tatsumi, Hideaki Shimada, Kenzo Hiroshima, Masatoshi Tagawa
Published 2013-01-01