Loss of highwire Protects Against the Deleterious Effects of Traumatic Brain Injury in Drosophila Melanogaster

Traumatic brain injury is a major global cause of death and disability. Axonal injury is a major underlying mechanism of TBI and could represent a major therapeutic target. We provide evidence that targeting the axonal death pathway known as Wallerian degeneration improves outcome in a Drosophila Me...

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Bibliographic Details
Main Authors: Ciaran S. Hill, Jemeen Sreedharan, Andrea Loreto, David K. Menon, Michael P. Coleman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00401/full