Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population—an analysis from the MEMO study

Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population—an analysis from the MEMO study

Abstract Background Neurofilament light chain (NfL) is a cytoskeletal protein component whose release into blood is indicative of neuronal damage. Tau is a microtubule-associated protein in neurons and strongly associated with overall brain degeneration. NfL and tau levels are associated with mortal...

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Bibliographic Details
Main Authors: Nicole Rübsamen, Aleksandra Maceski, David Leppert, Pascal Benkert, Jens Kuhle, Heinz Wiendl, Annette Peters, André Karch, Klaus Berger
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Medicine
Subjects:
Biomarker
Mortality
Neurofilament
Prognosis
SIMOA
Tau
Online Access:https://doi.org/10.1186/s12916-021-01915-8

Internet

https://doi.org/10.1186/s12916-021-01915-8

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