Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis

by Ngoc Dung Le, Lukas Muri, Denis Grandgirard, Jens Kuhle, David Leppert, Stephen L. Leib
Published 2020-10-01

Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population—an analysis from the MEMO study

by Nicole Rübsamen, Aleksandra Maceski, David Leppert, Pascal Benkert, Jens Kuhle, Heinz Wiendl, Annette Peters, André Karch, Klaus Berger
Published 2021-02-01

Blood neurofilament light as a potential endpoint in Phase 2 studies in MS

by Maria Pia Sormani, Dieter A. Haering, Harald Kropshofer, David Leppert, Uma Kundu, Christian Barro, Ludwig Kappos, Davorka Tomic, Jens Kuhle
Published 2019-06-01

Ratio and index of Neurofilament light chain indicate its origin in Guillain‐Barré Syndrome

by Peter Körtvelyessy, Jens Kuhle, Emrah Düzel, Stefan Vielhaber, Christian Schmidt, Annika Heinius, Frank Leypoldt, Burkhart Schraven, Dirk Reinhold, David Leppert, Alexander Goihl
Published 2020-11-01

Serum neurofilament light levels in normal aging and their association with morphologic brain changes

by Michael Khalil, Lukas Pirpamer, Edith Hofer, Margarete M. Voortman, Christian Barro, David Leppert, Pascal Benkert, Stefan Ropele, Christian Enzinger, Franz Fazekas, Reinhold Schmidt, Jens Kuhle
Published 2020-02-01

Temporal association of sNfL and gad‐enhancing lesions in multiple sclerosis

by Mattia Rosso, Cindy T. Gonzalez, Brian C. Healy, Shrishti Saxena, Anu Paul, Kjetil Bjornevik, Jens Kuhle, Pascal Benkert, David Leppert, Charles Guttmann, Rohit Bakshi, Howard L. Weiner, Tanuja Chitnis
Published 2020-06-01

Serum neurofilament measurement improves clinical risk scores for outcome prediction after cardiac arrest: results of a prospective study

by Sabina Hunziker, Adrian Quinto, Maja Ramin-Wright, Christoph Becker, Katharina Beck, Alessia Vincent, Kai Tisljar, Giulio Disanto, Pascal Benkert, David Leppert, Hans Pargger, Stephan Marsch, Raoul Sutter, Nils Peters, Jens Kuhle
Published 2021-01-01

Serum neurofilament light chain levels associations with gray matter pathology: a 5‐year longitudinal study

by Dejan Jakimovski, Jens Kuhle, Murali Ramanathan, Christian Barro, Davorka Tomic, Jesper Hagemeier, Harald Kropshofer, Niels Bergsland, David Leppert, Michael G. Dwyer, Zuzanna Michalak, Ralph H. B. Benedict, Bianca Weinstock‐Guttman, Robert Zivadinov
Published 2019-09-01

Increased neurofilament light chain blood levels in neurodegenerative neurological diseases.

by Johanna Gaiottino, Niklas Norgren, Ruth Dobson, Joanne Topping, Ahuva Nissim, Andrea Malaspina, Jonathan P Bestwick, Andreas U Monsch, Axel Regeniter, Raija L Lindberg, Ludwig Kappos, David Leppert, Axel Petzold, Gavin Giovannoni, Jens Kuhle
Published 2013-01-01

Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder

by Patrick Schindler, Ulrike Grittner, Johanna Oechtering, David Leppert, Nadja Siebert, Ankelien S. Duchow, Frederike C. Oertel, Susanna Asseyer, Joseph Kuchling, Hanna G. Zimmermann, Alexander U. Brandt, Pascal Benkert, Markus Reindl, Sven Jarius, Friedemann Paul, Judith Bellmann-Strobl, Jens Kuhle, Klemens Ruprecht
Published 2021-05-01

Imaging Mass Cytometry and Single-Cell Genomics Reveal Differential Depletion and Repletion of B-Cell Populations Following Ofatumumab Treatment in Cynomolgus Monkeys

by Diethilde Theil, Paul Smith, Catherine Huck, Yoann Gilbart, Algirdas Kakarieka, David Leppert, Celine Rauld, Cindy Schmid, Reto Baumgartner, Nathalie Stuber, Francisco Cordoba, Valerie Dubost, Katy Darribat, Magali Jivkov, Wilfried Frieauff, Rainer Kneuer, Markus Stoeckli, Stefan Reinker, Keith Mansfield, José M. Carballido, Philippe Couttet, Gisbert Weckbecker
Published 2019-06-01