The A4 study: β‐amyloid and cognition in 4432 cognitively unimpaired adults

Abstract Objective To clarify the preclinical stage of Alzheimer’s disease by estimating when β‐amyloid accumulation first becomes associated with changes in cognition. Methods Here we studied a large group (N = 4432) of cognitively unimpaired individuals who were screened for inclusion in the A4 tr...

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Bibliographic Details
Main Authors: Philip S. Insel, Michael C. Donohue, Reisa Sperling, Oskar Hansson, Niklas Mattsson‐Carlgren
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.51048