Monocyte scintigraphy in rheumatoid arthritis: the dynamics of monocyte migration in immune-mediated inflammatory disease.

BACKGROUND:Macrophages are principal drivers of synovial inflammation in rheumatoid arthritis (RA), a prototype immune-mediated inflammatory disease. Conceivably, synovial macrophages are continuously replaced by circulating monocytes in RA. Animal studies from the 1960s suggested that macrophage re...

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Bibliographic Details
Main Authors: Rogier M Thurlings, Carla A Wijbrandts, Roelof J Bennink, Serge E Dohmen, Carlijn Voermans, Diana Wouters, Elena S Izmailova, Danielle M Gerlag, Berthe L F van Eck-Smit, Paul P Tak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2773010?pdf=render