Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes

by Mischa P. Keizer, Mischa P. Keizer, Angela Kamp, Gerard van Mierlo, Taco W. Kuijpers, Taco W. Kuijpers, Diana Wouters
Published 2018-06-01

Anaphylatoxin C5a Regulates 6-Sulfo-LacNAc Dendritic Cell Function in Human through Crosstalk with Toll-Like Receptor-Induced CREB Signaling

by Anouk Zaal, Anouk Zaal, Miranda Dieker, Miranda Dieker, Manon Oudenampsen, Manon Oudenampsen, Annelies W. Turksma, Annelies W. Turksma, Suzanne N. Lissenberg-Thunnissen, Suzanne N. Lissenberg-Thunnissen, Diana Wouters, Diana Wouters, S. Marieke van Ham, S. Marieke van Ham, Anja ten Brinke, Anja ten Brinke
Published 2017-07-01

Complement Factor H-Related Protein 3 Serum Levels Are Low Compared to Factor H and Mainly Determined by Gene Copy Number Variation in CFHR3.

by Richard B Pouw, Mieke C Brouwer, Judy Geissler, Laurens V van Herpen, Sacha S Zeerleder, Walter A Wuillemin, Diana Wouters, Taco W Kuijpers
Published 2016-01-01

Increased Nucleosomes and Neutrophil Activation Link to Disease Progression in Patients with Scrub Typhus but Not Murine Typhus in Laos.

by Daniel H Paris, Femke Stephan, Ingrid Bulder, Diana Wouters, Tom van der Poll, Paul N Newton, Nicholas P J Day, Sacha Zeerleder
Published 2015-01-01

Sugar Matters: Improving In Vivo Clearance Rate of Highly Glycosylated Recombinant Plasma Proteins for Therapeutic Use

by Sacha Zeerleder, Ruchira Engel, Tao Zhang, Dorina Roem, Gerard van Mierlo, Ineke Wagenaar-Bos, Sija Marieke van Ham, Manfred Wuhrer, Diana Wouters, Ilse Jongerius
Published 2021-01-01

The high prevalence of functional complement defects induced by chemotherapy

by Mischa P Keizer, Mischa P Keizer, Angela Kamp, Cathelijn Aarts, Judy Geisler, Huib Caron, Marianne van de Wetering, Diana Wouters, Taco Kuijpers, Taco Kuijpers
Published 2016-10-01

Corrigendum: High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3*B

by Richard B. Pouw, Richard B. Pouw, Irene Gómez Delgado, Alberto López Lera, Santiago Rodríguez de Córdoba, Diana Wouters, Taco W. Kuijpers, Taco W. Kuijpers, Pilar Sánchez-Corral
Published 2020-01-01

High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3*B

by Richard B. Pouw, Richard B. Pouw, Irene Gómez Delgado, Alberto López Lera, Santiago Rodríguez de Córdoba, Diana Wouters, Taco W. Kuijpers, Taco W. Kuijpers, Pilar Sánchez-Corral
Published 2018-04-01

Complement Factor H-Related Protein 4A Is the Dominant Circulating Splice Variant of CFHR4

by Richard B. Pouw, Richard B. Pouw, Mieke C. Brouwer, Anna E. van Beek, Anna E. van Beek, Mihály Józsi, Diana Wouters, Taco W. Kuijpers, Taco W. Kuijpers
Published 2018-04-01

Systemic complement activation in central serous chorioretinopathy.

by Elon H C van Dijk, Roula Tsonaka, Ngaisah Klar-Mohamad, Diana Wouters, Aiko P J de Vries, Eiko K de Jong, Cees van Kooten, Camiel J F Boon
Published 2017-01-01

Monocyte scintigraphy in rheumatoid arthritis: the dynamics of monocyte migration in immune-mediated inflammatory disease.

by Rogier M Thurlings, Carla A Wijbrandts, Roelof J Bennink, Serge E Dohmen, Carlijn Voermans, Diana Wouters, Elena S Izmailova, Danielle M Gerlag, Berthe L F van Eck-Smit, Paul P Tak
Published 2009-11-01

Reference Intervals of Factor H and Factor H-Related Proteins in Healthy Children

by Anna E. van Beek, Anna E. van Beek, Angela Kamp, Simone Kruithof, Ed J. Nieuwenhuys, Diana Wouters, Ilse Jongerius, Theo Rispens, Taco W. Kuijpers, Taco W. Kuijpers, Kyra A. Gelderman
Published 2018-08-01

COMPLEMENT REGULATOR FHR-3 IS ELEVATED EITHER LOCALLY OR SYSTEMICALLY IN A SELECTION OF AUTOIMMUNE DISEASES

by Nicole Schäfer, Antje Grosche, Joerg Reinders, Stefanie Hauck, Richard B. Pouw, Taco W. Kuijpers, Taco W. Kuijpers, Diana Wouters, Boris Ehrenstein, Volker Enzmann, Peter Zipfel, Peter Zipfel, Christine Skerka, Diana Pauly
Published 2016-11-01

Human plasma-derived C1 esterase inhibitor concentrate has limited effect on house dust mite-induced allergic lung inflammation in mice.

by Ingrid Stroo, Jack Yang, Adam A Anas, J Daan de Boer, Gerard van Mierlo, Dorina Roem, Diana Wouters, Ruchira Engel, Joris J T H Roelofs, Cornelis van 't Veer, Tom van der Poll, Sacha Zeerleder
Published 2017-01-01

The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients

by Friso M. de Beer, Luuk Wieske, Gerard van Mierlo, Diana Wouters, Sacha Zeerleder, Lieuwe D. Bos, Nicole P. Juffermans, Marcus J. Schultz, Tom van der Poll, Wim K. Lagrand, Janneke Horn, for the BASIC–study group
Published 2020-12-01

Complement factor H contributes to mortality in humans and mice with bacterial meningitis

by E. Soemirien Kasanmoentalib, Mercedes Valls Serón, Joo Yeon Engelen-Lee, Michael W. Tanck, Richard B. Pouw, Gerard van Mierlo, Diana Wouters, Matthew C. Pickering, Arie van der Ende, Taco W. Kuijpers, Matthijs C. Brouwer, Diederik van de Beek
Published 2019-12-01

Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma

by Anna E. van Beek, Anna E. van Beek, Richard B. Pouw, Richard B. Pouw, Mieke C. Brouwer, Gerard van Mierlo, Judy Geissler, Pleuni Ooijevaar-de Heer, Martin de Boer, Karin van Leeuwen, Theo Rispens, Diana Wouters, Taco W. Kuijpers, Taco W. Kuijpers
Published 2017-10-01

Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities

by Gillian Dekkers, Louise Treffers, Rosina Plomp, Arthur E. H. Bentlage, Marcella de Boer, Carolien A. M. Koeleman, Suzanne N. Lissenberg-Thunnissen, Remco Visser, Mieke Brouwer, Juk Yee Mok, Hanke Matlung, Timo K. van den Berg, Wim J. E. van Esch, Taco W. Kuijpers, Diana Wouters, Theo Rispens, Manfred Wuhrer, Gestur Vidarsson
Published 2017-08-01