A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis

The voltage-gated potassium channel Kv1.3 plays an apparent dual physiological role by participating in activation and proliferation of leukocytes as well as promoting apoptosis in several types of tumor cells. Therefore, Kv1.3 is considered a potential pharmacological target for immunodeficiency an...

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Bibliographic Details
Main Authors: Jesusa Capera, Mireia Pérez-Verdaguer, Roberta Peruzzo, María Navarro-Pérez, Juan Martínez-Pinna, Armando Alberola-Die, Andrés Morales, Luigi Leanza, Ildiko Szabó, Antonio Felipe
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/69099