Mitochondrial Kv1.3: a New Target in Cancer Biology?

by Vanessa Checchetto, Elena Prosdocimi, Luigi Leanza
Published 2019-12-01

Mitochondrial Metabolism, Contact Sites and Cellular Calcium Signaling: Implications for Tumorigenesis

by Roberta Peruzzo, Roberto Costa, Magdalena Bachmann, Luigi Leanza, Ildikò Szabò
Published 2020-09-01

Biophysical Characterization and Expression Analysis of Kv1.3 Potassium Channel in Primary Human Leukemic B Cells

by Ildiko Szabo, Livio Trentin, Valentina Trimarco, Gianpietro Semenzato, Luigi Leanza
Published 2015-09-01

Mitochondrial Dynamics, ROS, and Cell Signaling: A Blended Overview

by Valentina Brillo, Leonardo Chieregato, Luigi Leanza, Silvia Muccioli, Roberto Costa
Published 2021-04-01

Targeting Mitochondrial Ion Channels to Fight Cancer

by Magdalena Bachmann, Roberto Costa, Roberta Peruzzo, Elena Prosdocimi, Vanessa Checchetto, Luigi Leanza
Published 2018-07-01

From Channels to Canonical Wnt Signaling: A Pathological Perspective

by Silvia Muccioli, Valentina Brillo, Leonardo Chieregato, Luigi Leanza, Vanessa Checchetto, Roberto Costa
Published 2021-04-01

NMR Metabolite Profiles of the Bivalve Mollusc Mytilus galloprovincialis Before and After Immune Stimulation With Vibrio splendidus

by Riccardo Frizzo, Enrico Bortoletto, Tobia Riello, Luigi Leanza, Elisabetta Schievano, Paola Venier, Stefano Mammi
Published 2021-09-01

Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells

by Roberta Peruzzo, Andrea Mattarei, Matteo Romio, Cristina Paradisi, Mario Zoratti, Mario Zoratti, Ildikò Szabò, Ildikò Szabò, Luigi Leanza
Published 2017-09-01

Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents

by Andrea Mattarei, Matteo Romio, Antonella Managò, Mario Zoratti, Mario Zoratti, Cristina Paradisi, Ildikò Szabò, Luigi Leanza, Lucia Biasutto, Lucia Biasutto
Published 2018-04-01

Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs

by Vitalyi Senyuk, Najmeh Eskandari, Ying Jiang, Rebeca Garcia-Varela, Rachel Sundstrom, Luigi Leanza, Roberta Peruzzo, Mark Burkard, Richard D. Minshall, Saverio Gentile
Published 2021-09-01

A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis

by Jesusa Capera, Mireia Pérez-Verdaguer, Roberta Peruzzo, María Navarro-Pérez, Juan Martínez-Pinna, Armando Alberola-Die, Andrés Morales, Luigi Leanza, Ildiko Szabó, Antonio Felipe
Published 2021-07-01

Excessive Accumulation of Ca2 + in Mitochondria of Y522S-RYR1 Knock-in Mice: A Link Between Leak From the Sarcoplasmic Reticulum and Altered Redox State

by Marta Canato, Paola Capitanio, Lina Cancellara, Luigi Leanza, Anna Raffaello, Denis Vecellio Reane, Lorenzo Marcucci, Antonio Michelucci, Antonio Michelucci, Feliciano Protasi, Feliciano Protasi, Carlo Reggiani, Carlo Reggiani
Published 2019-09-01

Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells

by Elisa Venturini, Luigi Leanza, Michele Azzolini, Stephanie Kadow, Andrea Mattarei, Michael Weller, Ghazaleh Tabatabai, Michael J. Edwards, Mario Zoratti, Cristina Paradisi, Ildikò Szabò, Erich Gulbins, Katrin Anne Becker
Published 2017-09-01

Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction

by Roberta Peruzzo, Samantha Corrà, Roberto Costa, Michele Brischigliaro, Tatiana Varanita, Lucia Biasutto, Chiara Rampazzo, Daniele Ghezzi, Luigi Leanza, Mario Zoratti, Massimo Zeviani, Cristiano De Pittà, Carlo Viscomi, Rodolfo Costa, Ildikò Szabò
Published 2021-04-01

Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates

by Federica Rossin, Roberto Costa, Matteo Bordi, Manuela D’Eletto, Luca Occhigrossi, Maria Grazia Farrace, Nickolai Barlev, Fabiola Ciccosanti, Silvia Muccioli, Leonardo Chieregato, Ildiko Szabo, Gian Maria Fimia, Mauro Piacentini, Luigi Leanza
Published 2021-03-01

Inhibition of PI-3-K and AKT Amplifies Kv1.3 Inhibitor-Induced Death of Human T Leukemia Cells

by Tim Bergermann, Lukas Born, Fiona Ferguson, Paula Latkovic, Alexandra Scheul, Nina Sonnenschein, Luigi Leanza, Simone Keitsch, Carolin Sehl, Barbara Wilker, Michael J. Edwards, Mario Zoratti, Cristina Paradisi, Markus Kohnen, Ildiko Szabo, Katrin Anne Becker, Alexander Carpinteiro
Published 2019-12-01

Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

by Roberto Costa, Roberta Peruzzo, Magdalena Bachmann, Giulia Dalla Montà, Mattia Vicario, Giulia Santinon, Andrea Mattarei, Enrico Moro, Rubén Quintana-Cabrera, Luca Scorrano, Massimo Zeviani, Francesca Vallese, Mario Zoratti, Cristina Paradisi, Francesco Argenton, Marisa Brini, Tito Calì, Sirio Dupont, Ildikò Szabò, Luigi Leanza
Published 2019-08-01

Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family

by Roberta Peruzzo, Andrea Mattarei, Michele Azzolini, Katrin Anne Becker-Flegler, Matteo Romio, Giovanni Rigoni, Andrea Carrer, Lucia Biasutto, Sofia Parrasia, Stephanie Kadow, Antonella Managò, Andrea Urbani, Andrea Rossa, Gianpietro Semenzato, Maria Eugenia Soriano, Livio Trentin, Syed Ahmad, Michael Edwards, Erich Gulbins, Cristina Paradisi, Mario Zoratti, Luigi Leanza, Ildikò Szabò
Published 2020-10-01

Corrigendum to “Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family” [Redox B...

by Roberta Peruzzo, Andrea Mattarei, Michele Azzolini, Katrin Anne Becker-Flegler, Matteo Romio, Giovanni Rigoni, Andrea Carrer, Lucia Biasutto, Sofia Parrasia, Stephanie Kadow, Antonella Managò, Andrea Urbani, Andrea Rossa, Gianpietro Semenzato, Maria Eugenia Soriano, Livio Trentin, Syed Ahmad, Michael Edwards, Erich Gulbins, Cristina Paradisi, Mario Zoratti, Luigi Leanza, Ildikò Szabò
Published 2021-09-01