Meta-Apo improves accuracy of 16S-amplicon-based prediction of microbiome function

Abstract Background Due to their much lower costs in experiment and computation than metagenomic whole-genome sequencing (WGS), 16S rRNA gene amplicons have been widely used for predicting the functional profiles of microbiome, via software tools such as PICRUSt 2. However, due to the potential PCR...

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Bibliographic Details
Main Authors: Gongchao Jing, Yufeng Zhang, Wenzhi Cui, Lu Liu, Jian Xu, Xiaoquan Su
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-020-07307-1