Optimizing metabolite production using periodic oscillations.

Methods for improving microbial strains for metabolite production remain the subject of constant research. Traditionally, metabolic tuning has been mostly limited to knockouts or overexpression of pathway genes and regulators. In this paper, we establish a new method to control metabolism by inducin...

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Bibliographic Details
Main Authors: Steven W Sowa, Michael Baldea, Lydia M Contreras
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4046915?pdf=render