Spatial Distance Correlates With Genetic Distance in Diffuse Glioma

Background: Treatment effectiveness and overall prognosis for glioma patients depend heavily on the genetic and epigenetic factors in each individual tumor. However, intra-tumoral genetic heterogeneity is known to exist and needs to be managed. Currently, evidence for genetic changes varying spatial...

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Bibliographic Details
Main Authors: Evan D. H. Gates, Jie Yang, Kazutaka Fukumura, Jonathan S. Lin, Jeffrey S. Weinberg, Sujit S. Prabhu, Lihong Long, David Fuentes, Erik P. Sulman, Jason T. Huse, Dawid Schellingerhout
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00676/full