Differential DNA Methylation Analysis without a Reference Genome

Differential DNA Methylation Analysis without a Reference Genome

Genome-wide DNA methylation mapping uncovers epigenetic changes associated with animal development, environmental adaptation, and species evolution. To address the lack of high-throughput methods for DNA methylation analysis in non-model organisms, we developed an integrated approach for studying DN...

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Bibliographic Details
Main Authors: Johanna Klughammer, Paul Datlinger, Dieter Printz, Nathan C. Sheffield, Matthias Farlik, Johanna Hadler, Gerhard Fritsch, Christoph Bock
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Cell Reports
Subjects:
DNA methylation
differential methylation analysis
bisulfite sequencing
RRBS
reference genome independent analysis
non-model organisms
cross-species comparison
comparative genomics
vertebrate genomes
computational epigenetics
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715013248

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http://www.sciencedirect.com/science/article/pii/S2211124715013248

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