A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells

A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells

Analyzing memory B cell repertoires of the healthy elderly enabled Michalon et al. to develop a recombinant human antibody selective for transthyretin amyloid. This antibody removes cardiac amyloid through recruitment of phagocytic immune cells.

Bibliographic Details
Main Authors: Aubin Michalon, Andreas Hagenbuch, Christian Huy, Evita Varela, Benoit Combaluzier, Thibaud Damy, Ole B. Suhr, Maria J. Saraiva, Christoph Hock, Roger M. Nitsch, Jan Grimm
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23274-x

Internet

https://doi.org/10.1038/s41467-021-23274-x

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