Transthyretin protects against A-beta peptide toxicity by proteolytic cleavage of the peptide: a mechanism sensitive to the Kunitz protease inhibitor.

by Rita Costa, Frederico Ferreira-da-Silva, Maria J Saraiva, Isabel Cardoso
Published 2008-01-01

Distinct annular oligomers captured along the assembly and disassembly pathways of transthyretin amyloid protofibrils.

by Ricardo H Pires, Árpád Karsai, Maria J Saraiva, Ana M Damas, Miklós S Z Kellermayer
Published 2012-01-01

A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells

by Aubin Michalon, Andreas Hagenbuch, Christian Huy, Evita Varela, Benoit Combaluzier, Thibaud Damy, Ole B. Suhr, Maria J. Saraiva, Christoph Hock, Roger M. Nitsch, Jan Grimm
Published 2021-05-01