Discovery of a dual protease mechanism that promotes DNA damage checkpoint recovery.

The DNA damage response is a signaling pathway found throughout biology. In many bacteria the DNA damage checkpoint is enforced by inducing expression of a small, membrane bound inhibitor that delays cell division providing time to repair damaged chromosomes. How cells promote checkpoint recovery af...

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Bibliographic Details
Main Authors: Peter E Burby, Zackary W Simmons, Jeremy W Schroeder, Lyle A Simmons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC6051672?pdf=render