MYR1-Dependent Effectors Are the Major Drivers of a Host Cell’s Early Response to Toxoplasma, Including Counteracting MYR1-Independent Effects

The obligate intracellular parasite Toxoplasma gondii controls its host cell from within the parasitophorous vacuole (PV) by using a number of diverse effector proteins, a subset of which require the aspartyl protease 5 enzyme (ASP5) and/or the recently discovered MYR1 protein to cross the PV membra...

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Bibliographic Details
Main Authors: Adit Naor, Michael W. Panas, Nicole Marino, Michael J. Coffey, Christopher J. Tonkin, John C. Boothroyd, Louis M. Weiss
Format: Article
Language:English
Published: American Society for Microbiology 2018-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/2/e02401-17