Interlaboratory validation of cerebrospinal fluid α‐synuclein quantification in the diagnosis of sporadic Creutzfeldt‐Jakob disease

Interlaboratory validation of cerebrospinal fluid α‐synuclein quantification in the diagnosis of sporadic Creutzfeldt‐Jakob disease

Abstract Introduction Cerebrospinal fluid α‐synuclein level is increased in sporadic Creutzfeldt‐Jakob disease cases. However, the clinical value of this biomarker remains to be established. In this study, we have addressed the clinical validation parameters and the interlaboratory reproducibility b...

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Bibliographic Details
Main Authors: Niels Kruse, Amanda Heslegrave, Vandana Gupta, Martha Foiani, Anna Villar‐Piqué, Matthias Schmitz, Sylvain Lehmann, Charlotte Teunissen, Kaj Blennow, Henrik Zetterberg, Brit Mollenhauer, Inga Zerr, Franc Llorens
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
Sporadic Creutzfeldt‐Jakob disease
α‐Synuclein
Cerebrospinal fluid
Biomarker
Diagnostic accuracy
Interlaboratory reproducibility
Online Access:https://doi.org/10.1016/j.dadm.2018.06.005

Internet

https://doi.org/10.1016/j.dadm.2018.06.005

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