The transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress.

The transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress.

Pathogenic Leptospira spp. are the causative agents of the waterborne zoonotic disease leptospirosis. Leptospira are challenged by numerous adverse conditions, including deadly reactive oxygen species (ROS), when infecting their hosts. Withstanding ROS produced by the host innate immunity is an impo...

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Bibliographic Details
Main Authors: Crispin Zavala-Alvarado, Odile Sismeiro, Rachel Legendre, Hugo Varet, Giovanni Bussotti, Jan Bayram, Samuel G Huete, Guillaume Rey, Jean-Yves Coppée, Mathieu Picardeau, Nadia Benaroudj
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008904

Internet

https://doi.org/10.1371/journal.ppat.1008904

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