Characterization of the various functional pathways elicited by synthetic agonists or antagonists at the melatonin MT1 and MT2 receptors

Characterization of the various functional pathways elicited by synthetic agonists or antagonists at the melatonin MT1 and MT2 receptors

Abstract Melatonin is a neurohormone that translates the circadian rhythm to the peripheral organs through a series of binding sites identified as G protein‐coupled receptors MT1 and MT2. Due to minute amounts of receptor proteins in target organs, the main tool of studies of the melatoninergic syst...

Full description

Bibliographic Details
Main Authors: Céline Legros, Clémence Dupré, Chantal Brasseur, Anne Bonnaud, Olivier Bruno, Damien Valour, Preety Shabajee, Adeline Giganti, Olivier Nosjean, Terrence P. Kenakin, Jean A. Boutin
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Pharmacology Research & Perspectives
Subjects:
biased ligands
melatonin
melatonin receptors
signaling pathways
Online Access:https://doi.org/10.1002/prp2.539

Internet

https://doi.org/10.1002/prp2.539

Similar Items