Prolonged calcitonin receptor signaling by salmon, but not human calcitonin, reveals ligand bias.

by Kim Vietz Andreassen, Sara Toftegaard Hjuler, Sebastian G Furness, Patrick M Sexton, Arthur Christopoulos, Olivier Nosjean, Morten Asser Karsdal, Kim Henriksen
Published 2014-01-01

Characterization of the Mel1c melatoninergic receptor in platypus (Ornithorhynchus anatinus).

by Célia Gautier, Sophie-Penelope Guenin, Isabelle Riest-Fery, Tahlia Jade Perry, Céline Legros, Olivier Nosjean, Valerie Simonneaux, Frank Grützner, Jean A Boutin
Published 2018-01-01

High-throughput screening for GPR119 modulators identifies a novel compound with anti-diabetic efficacy in db/db mice.

by Meng Zhang, Yang Feng, Jia Wang, Jianwei Zhao, Ting Li, Min He, Dehua Yang, Olivier Nosjean, Jean Boutin, Pierre Renard, Ming-Wei Wang
Published 2013-01-01

Recombinant human melatonin receptor MT1 isolated in mixed detergents shows pharmacology similar to that in mammalian cell membranes.

by Christel Logez, Sylvie Berger, Céline Legros, Jean-Louis Banères, William Cohen, Philippe Delagrange, Olivier Nosjean, Jean A Boutin, Gilles Ferry, Frédéric Simonin, Renaud Wagner
Published 2014-01-01

Characterization of the various functional pathways elicited by synthetic agonists or antagonists at the melatonin MT1 and MT2 receptors

by Céline Legros, Clémence Dupré, Chantal Brasseur, Anne Bonnaud, Olivier Bruno, Damien Valour, Preety Shabajee, Adeline Giganti, Olivier Nosjean, Terrence P. Kenakin, Jean A. Boutin
Published 2020-02-01

Hamster Melatonin Receptors: Cloning and Binding Characterization of MT1 and Attempt to Clone MT2

by Célia Gautier, Emilie Dufour, Clémence Dupré, Giulia Lizzo, Sarah Caignard, Isabelle Riest-Fery, Chantal Brasseur, Céline Legros, Philippe Delagrange, Olivier Nosjean, Valérie Simonneaux, Jean A. Boutin, Sophie-Pénélope Guenin
Published 2018-07-01

New Radioligands for Describing the Molecular Pharmacology of MT1 and MT2 Melatonin Receptors

by Olivier Nosjean, Jean A. Boutin, Jean-Louis Brayer, Philippe Delagrange, Daniel-Henri Caignard, Gérald Guillaumet, Pascal Berthelot, François Lefoulon, Emmanuel Thomas, Franck Suzenet, Benoît Folleas, Saïd Yous, Werner Hassler, Teresa Grelak, Sandrine Pedragona-Moreau, Ulrich Matthey, Céline Legros
Published 2013-04-01