Low Phytanic Acid-Concentrated DHA Prevents Cognitive Deficit and Regulates Alzheimer Disease Mediators in an ApoE<sup>−/−</sup> Mice Experimental Model

Low Phytanic Acid-Concentrated DHA Prevents Cognitive Deficit and Regulates Alzheimer Disease Mediators in an ApoE<sup>−/−</sup> Mice Experimental Model

Alzheimer&#8217;s disease (AD) is the main cause of dementia and cognitive impairment. It has been associated with a significant diminution of omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA) levels in the brain. Clinical trials with DHA as a treatment in neurological diseases have...

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Bibliographic Details
Main Authors: María Belén Ruiz-Roso, Víctor Echeverry-Alzate, Baltasar Ruiz-Roso, José Carlos Quintela, Sandra Ballesteros, Vicente Lahera, Natalia de las Heras, José Antonio López-Moreno, Beatriz Martín-Fernández
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Nutrients
Subjects:
Alzheimer’s
DHA
ApoE<sup>−/−</sup>
phytanic acid
inflammation
neuroprotection
oxidation
Online Access:https://www.mdpi.com/2072-6643/11/1/11

Internet

https://www.mdpi.com/2072-6643/11/1/11

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