Gnathodiaphyseal dysplasia is not recapitulated in a respective mouse model carrying a mutation of the Ano5 gene

Gnathodiaphyseal dysplasia is not recapitulated in a respective mouse model carrying a mutation of the Ano5 gene

Mutations in the gene ANO5, encoding for the transmembrane protein Anoctamin 5 (Ano5), have been identified to cause gnathodiaphyseal dysplasia (GDD) in humans, a skeletal disorder characterized by sclerosis of tubular bones, increased fracture risk and fibro-osseous lesions of the jawbones. To bett...

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Bibliographic Details
Main Authors: Tim Rolvien, Osman Avci, Simon von Kroge, Till Koehne, Stefan Selbert, Stephan Sonntag, Doron Shmerling, Uwe Kornak, Ralf Oheim, Michael Amling, Thorsten Schinke, Timur Alexander Yorgan
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Bone Reports
Subjects:
Ano5
Gnathodiaphyseal dysplasia
Mouse model
Skeletal disorder
Online Access:http://www.sciencedirect.com/science/article/pii/S2352187220300413

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http://www.sciencedirect.com/science/article/pii/S2352187220300413

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