Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer

Background Accumulating evidence suggests immunomodulatory and context-dependent effects of TP53 mutations in cancer. We performed an exploratory analysis of the transcriptional, immunobiological and prognostic associations of TP53 mutations within the gene expression-based consensus molecular subty...

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Bibliographic Details
Main Authors: Jørgen Smeby, Anita Sveen, Christian H Bergsland, Ina A Eilertsen, Stine A Danielsen, Peter W Eide, Merete Hektoen, Marianne G Guren, Arild Nesbakken, Jarle Bruun, Ragnhild A Lothe
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:ESMO Open
Online Access:https://esmoopen.bmj.com/content/4/3/e000523.full