Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity

by Jørgen Smeby, Kushtrim Kryeziu, Kaja C.G. Berg, Ina A. Eilertsen, Peter W. Eide, Bjarne Johannessen, Marianne G. Guren, Arild Nesbakken, Jarle Bruun, Ragnhild A. Lothe, Anita Sveen
Published 2020-09-01

Increased sensitivity to SMAC mimetic LCL161 identified by longitudinal ex vivo pharmacogenomics of recurrent, KRAS mutated rectal cancer liver metastases

by Kushtrim Kryeziu, Seyed H. Moosavi, Christian H. Bergsland, Marianne G. Guren, Peter W. Eide, Max Z. Totland, Kristoffer Lassen, Andreas Abildgaard, Arild Nesbakken, Anita Sveen, Ragnhild A. Lothe
Published 2021-09-01

Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer

by Jørgen Smeby, Anita Sveen, Christian H Bergsland, Ina A Eilertsen, Stine A Danielsen, Peter W Eide, Merete Hektoen, Marianne G Guren, Arild Nesbakken, Jarle Bruun, Ragnhild A Lothe
Published 2019-06-01

Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer

by Peter W. Eide, Seyed H. Moosavi, Ina A. Eilertsen, Tuva H. Brunsell, Jonas Langerud, Kaja C. G. Berg, Bård I. Røsok, Bjørn A. Bjørnbeth, Arild Nesbakken, Ragnhild A. Lothe, Anita Sveen
Published 2021-07-01

Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer

by Jarle Bruun, Anita Sveen, Rita Barros, Peter W. Eide, Ina Eilertsen, Matthias Kolberg, Teijo Pellinen, Leonor David, Aud Svindland, Olli Kallioniemi, Marianne G. Guren, Arild Nesbakken, Raquel Almeida, Ragnhild A. Lothe
Published 2018-09-01

De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity

by Seyed H. Moosavi, Peter W. Eide, Ina A. Eilertsen, Tuva H. Brunsell, Kaja C. G. Berg, Bård I. Røsok, Kristoffer W. Brudvik, Bjørn A. Bjørnbeth, Marianne G. Guren, Arild Nesbakken, Ragnhild A. Lothe, Anita Sveen
Published 2021-09-01

The expressed mutational landscape of microsatellite stable colorectal cancers

by Anita Sveen, Bjarne Johannessen, Ina A. Eilertsen, Bård I. Røsok, Marie Gulla, Peter W. Eide, Jarle Bruun, Kushtrim Kryeziu, Leonardo A. Meza-Zepeda, Ola Myklebost, Bjørn A. Bjørnbeth, Rolf I. Skotheim, Arild Nesbakken, Ragnhild A. Lothe
Published 2021-09-01

Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies

by Kaja C. G. Berg, Peter W. Eide, Ina A. Eilertsen, Bjarne Johannessen, Jarle Bruun, Stine A. Danielsen, Merete Bjørnslett, Leonardo A. Meza-Zepeda, Mette Eknæs, Guro E. Lind, Ola Myklebost, Rolf I. Skotheim, Anita Sveen, Ragnhild A. Lothe
Published 2017-07-01