A computational systems biology software platform for multiscale modeling and simulation: Integrating whole-body physiology, disease biology, and molecular reaction networks

A computational systems biology software platform for multiscale modeling and simulation: Integrating whole-body physiology, disease biology, and molecular reaction networks

Today, in silico studies and trial simulations already complement experimental approaches in pharmaceutical R&D and have become indispensable tools for decision making and communication with regulatory agencies. While biology is multi-scale by nature, project work and software tools usually...

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Bibliographic Details
Main Authors: Thomas eEissing, Lars eKuepfer, Corina eBecker, Michael eBlock, Katrin eCoboeken, Thomas eGaub, Linus eGoerlitz, Juergen eJaeger, Roland eLoosen, Bernd eLudewig, Michaela eMeyer, Christoph eNiederalt, Michael eSevestre, Hans-Ulrich eSiegmund, Juri eSolodenko, Kirstin eThelen, Ulrich eTelle, Wolfgang eWeiss, Thomas eWendl, Stefan eWillmann, Joerg eLippert
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-02-01
Series:Frontiers in Physiology
Subjects:
Signal Transduction
Software
Systems Biology
simulation
modeling
PBPK
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00004/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00004/full

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