Physiologically-based pharmacokinetic modeling of tamoxifen and its metabolites in women of different CYP2D6 phenotypes provides new insight into the tamoxifen mass balance

by Kristin eDickschen, Kristin eDickschen, Stefan eWillmann, Kirstin eThelen, Jörg eLippert, Georg eHempel, Thomas eEissing
Published 2012-05-01

A computational systems biology software platform for multiscale modeling and simulation: Integrating whole-body physiology, disease biology, and molecular reaction networks

by Thomas eEissing, Lars eKuepfer, Corina eBecker, Michael eBlock, Katrin eCoboeken, Thomas eGaub, Linus eGoerlitz, Juergen eJaeger, Roland eLoosen, Bernd eLudewig, Michaela eMeyer, Christoph eNiederalt, Michael eSevestre, Hans-Ulrich eSiegmund, Juri eSolodenko, Kirstin eThelen, Ulrich eTelle, Wolfgang eWeiss, Thomas eWendl, Stefan eWillmann, Joerg eLippert
Published 2011-02-01