A Novel Admixture-Based Pharmacogenetic Approach to Refine Warfarin Dosing in Caribbean Hispanics.

AIM:This study is aimed at developing a novel admixture-adjusted pharmacogenomic approach to individually refine warfarin dosing in Caribbean Hispanic patients. PATIENTS & METHODS:A multiple linear regression analysis of effective warfarin doses versus relevant genotypes, admixture, clinical and...

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Main Authors: Jorge Duconge, Alga S Ramos, Karla Claudio-Campos, Giselle Rivera-Miranda, Luis Bermúdez-Bosch, Jessicca Y Renta, Carmen L Cadilla, Iadelisse Cruz, Juan F Feliu, Cunegundo Vergara, Gualberto Ruaño
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4706412?pdf=render