Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder in Puerto Rico

by Darlene Santiago, Victor Mangas-Sanjuan, Kyle Melin, Jorge Duconge, Wenchen Zhao, Raman Venkataramanan
Published 2020-12-01

Insight on the Genetics of Atrial Fibrillation in Puerto Rican Hispanics

by Ariel F. Gonzalez-Cordero, Jorge Duconge-Soler, Hilton Franqui-Rivera, Roberto Feliu-Maldonado, Abiel Roche-Lima, Israel Almodovar-Rivera
Published 2021-01-01

Selective ATP-Binding Cassette Subfamily C Gene Expression and Proinflammatory Mediators Released by BEAS-2B after PM2.5, Budesonide, and Cotreated Exposures

by Jarline Encarnación-Medina, Rosa I. Rodríguez-Cotto, Joseph Bloom-Oquendo, Mario G. Ortiz-Martínez, Jorge Duconge, Braulio Jiménez-Vélez
Published 2017-01-01

Physiologically-Based Pharmacokinetic/Pharmacodynamic Model of MBQ-167 to Predict Tumor Growth Inhibition in Mice

by Javier Reig-López, María del Mar Maldonado, Matilde Merino-Sanjuan, Ailed M. Cruz-Collazo, Jean F. Ruiz-Calderón, Victor Mangas-Sanjuán, Suranganie Dharmawardhane, Jorge Duconge
Published 2020-10-01

A Novel Admixture-Based Pharmacogenetic Approach to Refine Warfarin Dosing in Caribbean Hispanics.

by Jorge Duconge, Alga S Ramos, Karla Claudio-Campos, Giselle Rivera-Miranda, Luis Bermúdez-Bosch, Jessicca Y Renta, Carmen L Cadilla, Iadelisse Cruz, Juan F Feliu, Cunegundo Vergara, Gualberto Ruaño
Published 2016-01-01

Implementing a pharmacogenetic-driven algorithm to guide dual antiplatelet therapy (DAPT) in Caribbean Hispanics: protocol for a non-randomised clinical trial

by Dagmar F Hernandez-Suarez, Kyle Melin, Frances Marin-Maldonado, Hector J Nunez, Ariel F Gonzalez, Lorena Gonzalez-Sepulveda, Sona Rivas-Tumanyan, Hetanshi Naik, Gualberto Ruaño, Stuart A Scott, Jorge Duconge
Published 2020-08-01

Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study

by Karla Claudio-Campos, Aurora Labastida, Alga Ramos, Andrea Gaedigk, Jessicca Renta-Torres, Dariana Padilla, Giselle Rivera-Miranda, Stuart A. Scott, Stuart A. Scott, Gualberto Ruaño, Carmen L. Cadilla, Jorge Duconge-Soler
Published 2017-06-01

Machine Learning Algorithm for Predicting Warfarin Dose in Caribbean Hispanics Using Pharmacogenetic Data

by Abiel Roche-Lima, Adalis Roman-Santiago, Roberto Feliu-Maldonado, Jovaniel Rodriguez-Maldonado, Brenda G. Nieves-Rodriguez, Kelvin Carrasquillo-Carrion, Carla M. Ramos, Istoni da Luz Sant’Ana, Steven E. Massey, Jorge Duconge
Published 2020-01-01

A comparative pharmacokinetic and pharmacodynamic study of two novel Cuban PEGylated rHuEPO versus MIRCERA® and ior®EPOCIM

by Gledys Reynaldo, Leyanis Rodríguez, Roberto Menéndez, Joaquín Solazábal, Daniel Amaro, María de los A. Becquer, Yamila Colom, Haydee Gil, Juan C. Polo, Gilberto Castañeda, Braulio Jiménez-Vélez, Jorge Duconge, Eduardo M. Fernández-Sánchez
Published 2018-05-01

Potential of a Pharmacogenetic-Guided Algorithm to Predict Optimal Warfarin Dosing in a High-Risk Hispanic Patient

by Dagmar F. Hernandez-Suarez MD, Karla Claudio-Campos BSc, Javier E. Mirabal-Arroyo MD, Bianca A. Torres-Hernández PhD, Angel López-Candales MD, FACC, FASE, Kyle Melin PharmD, Jorge Duconge PhD, BScPharm
Published 2016-12-01

Clinical Relevant Polymorphisms Affecting Clopidogrel Pharmacokinetics and Pharmacodynamics: Insights from the Puerto Rico Newborn Screening Program

by Dagmar F. Hernandez-Suarez, Jonnalie C. Tomassini-Fernandini, Angelica Cuevas, Anyelis N. Rosario-Berrios, Héctor J. Nuñez-Medina, Dariana Padilla-Arroyo, Nannette Rivera, Jennifer Liriano, Rocio K. Vega-Roman, Jessicca Y. Renta, Kyle Melin, Jorge Duconge
Published 2018-05-01

Aporte farmacométrico en el desarrollo de productos biotecnológicos cubanos

by Gledys Reynaldo Fernández, Eduardo M. Fernández-Sánchez, Mayra Ramos Suzarte, Daniel Amaro, Roberto Menéndez, Helena Colom, Víctor Mangas-Sanjuan, Gilberto Castañeda, Jorge Duconge, Braulio Jiménez-Vélez, Niurys de Castro Suárez, Carmen Viada, Joaquín Solazábal, María de los A. Bécquer
Published 2020-12-01

Multi‐site Investigation of Genetic Determinants of Warfarin Dose Variability in Latinos

by Nihal El Rouby, Leiliane Rodrigues Marcatto, Karla Claudio, Letícia Camargo Tavares, Heidi Steiner, Marianna R. Botton, Steve A. Lubitz, Echo N. Fallon, Kevin Yee, Justin Kaye, Stuart A. Scott, Jason Karnes, Paulo Caleb Junior de Lima Santos, Jorge Duconge, Larisa H. Cavallari
Published 2021-01-01