Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters.

Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters.

The potential of broadly neutralizing antibodies targeting the HIV-1 envelope trimer to prevent HIV-1 transmission has opened new avenues for therapies and vaccines. However, their implementation remains challenging and would profit from a deepened mechanistic understanding of HIV-antibody interacti...

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Bibliographic Details
Main Authors: Oliver F Brandenberg, Carsten Magnus, Peter Rusert, Huldrych F Günthard, Roland R Regoes, Alexandra Trkola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5417720?pdf=render

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