Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters.
The potential of broadly neutralizing antibodies targeting the HIV-1 envelope trimer to prevent HIV-1 transmission has opened new avenues for therapies and vaccines. However, their implementation remains challenging and would profit from a deepened mechanistic understanding of HIV-antibody interacti...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-05-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC5417720?pdf=render |