Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels
Some ion channels are modulated by binding of cyclic nucleotide to a cyclic nucleotide-binding domain. Here, the authors use high-speed atomic force microscopy to directly monitor the conformational changes induced by ligand binding to a cyclic nucleotide-modulated channel from Mesorhizobium loti.
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2016-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms12789 |