Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel

by Philipp A. M. Schmidpeter, Jan Rheinberger, Crina M. Nimigean
Published 2020-12-01

Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures

by Jan Rheinberger, Xiaolong Gao, Philipp AM Schmidpeter, Crina M Nimigean
Published 2018-07-01

Real-time visualization of conformational changes within single MloK1 cyclic nucleotide-modulated channels

by Martina Rangl, Atsushi Miyagi, Julia Kowal, Henning Stahlberg, Crina M. Nimigean, Simon Scheuring
Published 2016-09-01

Mechanism of activation at the selectivity filter of the KcsA K+ channel

by Florian T Heer, David J Posson, Wojciech Wojtas-Niziurski, Crina M Nimigean, Simon Bernèche
Published 2017-10-01

Direct binding of phosphatidylglycerol at specific sites modulates desensitization of a ligand-gated ion channel

by Ailing Tong, John T Petroff II, Fong-Fu Hsu, Philipp AM Schmidpeter, Crina M Nimigean, Liam Sharp, Grace Brannigan, Wayland WL Cheng
Published 2019-11-01

Correlation of membrane protein conformational and functional dynamics

by Raghavendar Reddy Sanganna Gari, Joel José Montalvo‐Acosta, George R. Heath, Yining Jiang, Xiaolong Gao, Crina M. Nimigean, Christophe Chipot, Simon Scheuring
Published 2021-07-01

Identification of a pre-active conformation of a pentameric channel receptor

by Anaïs Menny, Solène N Lefebvre, Philipp AM Schmidpeter, Emmanuelle Drège, Zaineb Fourati, Marc Delarue, Stuart J Edelstein, Crina M Nimigean, Delphine Joseph, Pierre-Jean Corringer
Published 2017-03-01

Mechanistic insights into volatile anesthetic modulation of K2P channels

by Aboubacar Wague, Thomas T Joseph, Kellie A Woll, Weiming Bu, Kiran A Vaidya, Natarajan V Bhanu, Benjamin A Garcia, Crina M Nimigean, Roderic G Eckenhoff, Paul M Riegelhaupt
Published 2020-12-01

Structural basis of Ca2+-dependent activation and lipid transport by a TMEM16 scramblase

by Maria E Falzone, Jan Rheinberger, Byoung-Cheol Lee, Thasin Peyear, Linda Sasset, Ashleigh M Raczkowski, Edward T Eng, Annarita Di Lorenzo, Olaf S Andersen, Crina M Nimigean, Alessio Accardi
Published 2019-01-01