Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine Family

by Hideaki Hasegawa, Izuru Mizoguchi, Yukino Chiba, Mio Ohashi, Mingli Xu, Takayuki Yoshimoto
Published 2016-11-01

Regulation of Antitumor Immune Responses by the IL-12 Family Cytokines, IL-12, IL-23, and IL-27

by Mingli Xu, Izuru Mizoguchi, Noriko Morishima, Yukino Chiba, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2010-01-01

Prediction of Chemical Respiratory and Contact Sensitizers by OX40L Expression in Dendritic Cells Using a Novel 3D Coculture System

by Izuru Mizoguchi, Mio Ohashi, Yukino Chiba, Hideaki Hasegawa, Mingli Xu, Toshiyuki Owaki, Takayuki Yoshimoto
Published 2017-08-01

IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner.

by Yukino Chiba, Izuru Mizoguchi, Kana Mitobe, Kaname Higuchi, Hiroshi Nagai, Chikako Nishigori, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2013-01-01

A Pivotal Role for Interleukin-27 in CD8+ T Cell Functions and Generation of Cytotoxic T Lymphocytes

by Noriko Morishima, Izuru Mizoguchi, Masae Okumura, Yukino Chiba, Mingli Xu, Motomu Shimizu, Masanori Matsui, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2010-01-01

Protective effects against tumors and infection by interleukin-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors

by Naoko Orii, Izuru Mizoguchi, Yukino Chiba, Hideaki Hasegawa, Mio Ohashi, Mingli Xu, Taro Nagai, Nakaba Ochiai, Yuki Mochizuki, Toshiyuki Owaki, Takayuki Yoshimoto
Published 2018-05-01

Promotion of Expansion and Differentiation of Hematopoietic Stem Cells by Interleukin-27 into Myeloid Progenitors to Control Infection in Emergency Myelopoiesis.

by Jun-ichi Furusawa, Izuru Mizoguchi, Yukino Chiba, Masayuki Hisada, Fumie Kobayashi, Hiroki Yoshida, Susumu Nakae, Akihiko Tsuchida, Tetsuya Matsumoto, Hideo Ema, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2016-03-01