Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine Family

by Hideaki Hasegawa, Izuru Mizoguchi, Yukino Chiba, Mio Ohashi, Mingli Xu, Takayuki Yoshimoto
Published 2016-11-01

Regulation of Antitumor Immune Responses by the IL-12 Family Cytokines, IL-12, IL-23, and IL-27

by Mingli Xu, Izuru Mizoguchi, Noriko Morishima, Yukino Chiba, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2010-01-01

Prediction of Chemical Respiratory and Contact Sensitizers by OX40L Expression in Dendritic Cells Using a Novel 3D Coculture System

by Izuru Mizoguchi, Mio Ohashi, Yukino Chiba, Hideaki Hasegawa, Mingli Xu, Toshiyuki Owaki, Takayuki Yoshimoto
Published 2017-08-01

IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner.

by Yukino Chiba, Izuru Mizoguchi, Kana Mitobe, Kaname Higuchi, Hiroshi Nagai, Chikako Nishigori, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2013-01-01

A Pivotal Role for Interleukin-27 in CD8+ T Cell Functions and Generation of Cytotoxic T Lymphocytes

by Noriko Morishima, Izuru Mizoguchi, Masae Okumura, Yukino Chiba, Mingli Xu, Motomu Shimizu, Masanori Matsui, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2010-01-01

IL-23p19 and CD5 antigen-like form a possible novel heterodimeric cytokine and contribute to experimental autoimmune encephalomyelitis development

by Hideaki Hasegawa, Izuru Mizoguchi, Naoko Orii, Shinya Inoue, Yasuhiro Katahira, Toshihiko Yoneto, Mingli Xu, Toru Miyazaki, Takayuki Yoshimoto
Published 2021-03-01

Microbial Antigen-Presenting Extracellular Vesicles Derived from Genetically Modified Tumor Cells Promote Antitumor Activity of Dendritic Cells

by Tomoko Ito, Kikuya Sugiura, Aya Hasegawa, Wakana Ouchi, Takayuki Yoshimoto, Izuru Mizoguchi, Toshio Inaba, Katsuyuki Hamada, Masazumi Eriguchi, Yoshiyuki Koyama
Published 2021-01-01

Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases

by Ning Qu, Mingli Xu, Izuru Mizoguchi, Jun-ichi Furusawa, Kotaro Kaneko, Kazunori Watanabe, Junichiro Mizuguchi, Masahiro Itoh, Yutaka Kawakami, Takayuki Yoshimoto
Published 2013-01-01

Protective effects against tumors and infection by interleukin-27 through promotion of expansion and differentiation of hematopoietic stem cells into myeloid progenitors

by Naoko Orii, Izuru Mizoguchi, Yukino Chiba, Hideaki Hasegawa, Mio Ohashi, Mingli Xu, Taro Nagai, Nakaba Ochiai, Yuki Mochizuki, Toshiyuki Owaki, Takayuki Yoshimoto
Published 2018-05-01

Promotion of Expansion and Differentiation of Hematopoietic Stem Cells by Interleukin-27 into Myeloid Progenitors to Control Infection in Emergency Myelopoiesis.

by Jun-ichi Furusawa, Izuru Mizoguchi, Yukino Chiba, Masayuki Hisada, Fumie Kobayashi, Hiroki Yoshida, Susumu Nakae, Akihiko Tsuchida, Tetsuya Matsumoto, Hideo Ema, Junichiro Mizuguchi, Takayuki Yoshimoto
Published 2016-03-01

A Chaperone-Like Role for EBI3 in Collaboration With Calnexin Under Inflammatory Conditions

by Aruma Watanabe, Izuru Mizoguchi, Hideaki Hasegawa, Yasuhiro Katahira, Shinya Inoue, Eri Sakamoto, Yuma Furusaka, Ami Sekine, Satomi Miyakawa, Fumihiro Murakami, Mingli Xu, Toshihiko Yoneto, Takayuki Yoshimoto
Published 2021-09-01

Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege.

by Hayato Terayama, Takayuki Yoshimoto, Shuichi Hirai, Munekazu Naito, Ning Qu, Naoyuki Hatayama, Shogo Hayashi, Kana Mitobe, Jun-Ichi Furusawa, Izuru Mizoguchi, Takeshi Kezuka, Hiroshi Goto, Kaori Suyama, Hiroshi Moriyama, Kou Sakabe, Masahiro Itoh
Published 2014-01-01