Establishment of an In Vivo Xenograft Mouse Model of a Subcutaneous Submillimeter HT-29 Tumor Formed from a Single Spheroid Transplanted Using Radiation-Crosslinked Gelatin Hydroge...

by Tomoko Tachibana, Tomoko Gowa Oyama, Yukie Yoshii, Fukiko Hihara, Chika Igarashi, Atsushi B Tsuji, Tatsuya Higashi, Mitsumasa Taguchi
Published 2021-07-01

Preclinical Pharmacokinetic and Safety Studies of Copper-Diacetyl-Bis(N4-Methylthiosemicarbazone) (Cu-ATSM): Translational Studies for Internal Radiotherapy

by Hiroki Matsumoto, Yukie Yoshii, Atsumi Baden, Emi Kaneko, Hiroki Hashimoto, Hisashi Suzuki, Kazunori Kawamura, Ming-Rong Zhang, Tatsuya Higashi, Hiroaki Kurihara
Published 2019-09-01

Controlled administration of penicillamine reduces radiation exposure in critical organs during 64Cu-ATSM internal radiotherapy: a novel strategy for liver protection.

by Yukie Yoshii, Hiroki Matsumoto, Mitsuyoshi Yoshimoto, Takako Furukawa, Yukie Morokoshi, Chizuru Sogawa, Ming-Rong Zhang, Hidekatsu Wakizaka, Hiroshi Yoshii, Yasuhisa Fujibayashi, Tsuneo Saga
Published 2014-01-01

Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small an...

by Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Aya Sugyo, Yukie Yoshii, Kotaro Nagatsu, Ming-Rong Zhang, Yasuhisa Fujibayashi, Pascal Dumy, Didier Boturyn, Tatsuya Higashi
Published 2018-06-01

Multiple Administrations of 64Cu-ATSM as a Novel Therapeutic Option for Glioblastoma: a Translational Study Using Mice with Xenografts

by Yukie Yoshii, Hiroki Matsumoto, Mitsuyoshi Yoshimoto, Ming-Rong Zhang, Yoko Oe, Hiroaki Kurihara, Yoshitaka Narita, Zhao-Hui Jin, Atsushi B Tsuji, Keiichiro Yoshinaga, Yasuhisa Fujibayashi, Tatsuya Higashi
Published 2018-02-01

Fatty acid synthase is a key target in multiple essential tumor functions of prostate cancer: uptake of radiolabeled acetate as a predictor of the targeted therapy outcome.

by Yukie Yoshii, Takako Furukawa, Nobuyuki Oyama, Yoko Hasegawa, Yasushi Kiyono, Ryuichi Nishii, Atsuo Waki, Atsushi B Tsuji, Chizuru Sogawa, Hidekatsu Wakizaka, Toshimitsu Fukumura, Hiroshi Yoshii, Yasuhisa Fujibayashi, Jason S Lewis, Tsuneo Saga
Published 2013-01-01