Proof of Concept Study for Increasing Tenascin-C-Targeted Drug Delivery to Tumors Previously Subjected to Therapy: X-Irradiation Increases Tumor Uptake

by Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Kanako Takano, Moriaki Kusakabe, Tatsuya Higashi
Published 2020-12-01

Quantitative Radionuclide Imaging Analysis of Enhanced Drug Delivery Induced by Photoimmunotherapy

by Winn Aung, Atsushi B. Tsuji, Aya Sugyo, Masayuki Fujinaga, Ming-Rong Zhang, Tatsuya Higashi
Published 2021-08-01

Therapeutic efficacy of c-kit-targeted radioimmunotherapy using 90Y-labeled anti-c-kit antibodies in a mouse model of small cell lung cancer.

by Chisato Yoshida, Atsushi B Tsuji, Hitomi Sudo, Aya Sugyo, Tatsuya Kikuchi, Mitsuru Koizumi, Yasushi Arano, Tsuneo Saga
Published 2013-01-01

Simultaneous in vivo imaging with PET and SPECT tracers using a Compton-PET hybrid camera

by Mizuki Uenomachi, Miwako Takahashi, Kenji Shimazoe, Hiroyuki Takahashi, Kei Kamada, Tadashi Orita, Kenichiro Ogane, Atsushi B. Tsuji
Published 2021-09-01

Establishment of an In Vivo Xenograft Mouse Model of a Subcutaneous Submillimeter HT-29 Tumor Formed from a Single Spheroid Transplanted Using Radiation-Crosslinked Gelatin Hydroge...

by Tomoko Tachibana, Tomoko Gowa Oyama, Yukie Yoshii, Fukiko Hihara, Chika Igarashi, Atsushi B Tsuji, Tatsuya Higashi, Mitsumasa Taguchi
Published 2021-07-01

Single-Dose Cisplatin Pre-Treatment Enhances Efficacy of ROBO1-Targeted Radioimmunotherapy

by Kentaro Fujiwara, Keitaro Koyama, Atsushi B. Tsuji, Hiroko Iwanari, Osamu Kusano-Arai, Tatsuya Higashi, Toshimitsu Momose, Takao Hamakubo
Published 2020-10-01

In Vitro Evaluation of No-Carrier-Added Radiolabeled Cisplatin ([^{189, 191}Pt]cisplatin) Emitting Auger Electrons

by Honoka Obata, Atsushi B. Tsuji, Hitomi Sudo, Aya Sugyo, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, Ming-Rong Zhang
Published 2021-04-01

Radiolabeled Human Monoclonal Antibody 067-213 has the Potential for Noninvasive Quantification of CD73 Expression

by Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Gene Kurosawa, Yoshikazu Kurosawa, David Alexander, Hiroyuki Tsuda, Tsuneo Saga, Tatsuya Higashi
Published 2020-03-01

Evaluation of Efficacy of Radioimmunotherapy with 90Y-Labeled Fully Human Anti-Transferrin Receptor Monoclonal Antibody in Pancreatic Cancer Mouse Models.

by Aya Sugyo, Atsushi B Tsuji, Hitomi Sudo, Maki Okada, Mitsuru Koizumi, Hirokazu Satoh, Gene Kurosawa, Yoshikazu Kurosawa, Tsuneo Saga
Published 2015-01-01

Efficacy Evaluation of Combination Treatment Using Gemcitabine and Radioimmunotherapy with 90Y-Labeled Fully Human Anti-CD147 Monoclonal Antibody 059-053 in a BxPC-3 Xenograft Mous...

by Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Mitsuru Koizumi, Yoshinori Ukai, Gene Kurosawa, Yoshikazu Kurosawa, Tsuneo Saga, Tatsuya Higashi
Published 2018-09-01

Preclinical Evaluation of the Acute Radiotoxicity of the α-Emitting Molecular-Targeted Therapeutic Agent 211At-MABG for the Treatment of Malignant Pheochromocytoma in Normal Mice

by Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Kotaro Nagatsu, Katsuyuki Minegishi, Noriko S. Ishioka, Hiroshi Ito, Keiichiro Yoshinaga, Tatsuya Higashi
Published 2019-07-01

Evaluation of (89)Zr-labeled human anti-CD147 monoclonal antibody as a positron emission tomography probe in a mouse model of pancreatic cancer.

by Aya Sugyo, Atsushi B Tsuji, Hitomi Sudo, Kotaro Nagatsu, Mitsuru Koizumi, Yoshinori Ukai, Gene Kurosawa, Ming-Rong Zhang, Yoshikazu Kurosawa, Tsuneo Saga
Published 2013-01-01

Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small an...

by Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Aya Sugyo, Yukie Yoshii, Kotaro Nagatsu, Ming-Rong Zhang, Yasuhisa Fujibayashi, Pascal Dumy, Didier Boturyn, Tatsuya Higashi
Published 2018-06-01

Micro–Positron Emission Tomography/Contrast-Enhanced Computed Tomography Imaging of Orthotopic Pancreatic Tumor–Bearing Mice Using the αβ Integrin Tracer Cu-Labeled Cyclam-RAFT-c(-...

by Winn Aung, Zhao-Hui Jin, Takako Furukawa, Michael Claron, Didier Boturyn, Chizuru Sogawa, Atsushi B. Tsuji, Hidekatsu Wakizaka, Toshimitsu Fukumura, Yasuhisa Fujibayashi, Pascal Dumy, Tsuneo Saga
Published 2013-09-01

Multiple Administrations of 64Cu-ATSM as a Novel Therapeutic Option for Glioblastoma: a Translational Study Using Mice with Xenografts

by Yukie Yoshii, Hiroki Matsumoto, Mitsuyoshi Yoshimoto, Ming-Rong Zhang, Yoko Oe, Hiroaki Kurihara, Yoshitaka Narita, Zhao-Hui Jin, Atsushi B Tsuji, Keiichiro Yoshinaga, Yasuhisa Fujibayashi, Tatsuya Higashi
Published 2018-02-01

Fatty acid synthase is a key target in multiple essential tumor functions of prostate cancer: uptake of radiolabeled acetate as a predictor of the targeted therapy outcome.

by Yukie Yoshii, Takako Furukawa, Nobuyuki Oyama, Yoko Hasegawa, Yasushi Kiyono, Ryuichi Nishii, Atsuo Waki, Atsushi B Tsuji, Chizuru Sogawa, Hidekatsu Wakizaka, Toshimitsu Fukumura, Hiroshi Yoshii, Yasuhisa Fujibayashi, Jason S Lewis, Tsuneo Saga
Published 2013-01-01

Immuno-PET Imaging of HER3 in a Model in which HER3 Signaling Plays a Critical Role.

by Qinghua Yuan, Takako Furukawa, Takahiro Tashiro, Kouki Okita, Zhao-Hui Jin, Winn Aung, Aya Sugyo, Kotaro Nagatsu, Hiroko Endo, Atsushi B Tsuji, Ming-Rong Zhang, Takashi Masuko, Masahiro Inoue, Yasuhisa Fujibayashi, Tsuneo Saga
Published 2015-01-01

Immunotargeting of Integrin αβ for Single-Photon Emission Computed Tomography and Near-Infrared Fluorescence Imaging in a Pancreatic Cancer Model

by Winn Aung MBBS, PhD, Atsushi B. Tsuji PhD, Hitomi Sudo PhD, Aya Sugyo M.Ed, Takako Furukawa PhD, Yoshinori Ukai PhD, Yoshikazu Kurosawa PhD, Tsuneo Saga MD, PhD
Published 2016-01-01