Developing a Reliable Mouse Model for Cancer Therapy-Induced Cardiovascular Toxicity in Cancer Patients and Survivors

by Kyung Ae Ko, Yin Wang, Sivareddy Kotla, Yuka Fujii, Hang Thi Vu, Bhanu P. Venkatesulu, Tamlyn N. Thomas, Jan L. Medina, Young Jin Gi, Megumi Hada, Jane Grande-Allen, Zarana S. Patel, Sarah A. Milgrom, Sunil Krishnan, Keigi Fujiwara, Jun-Ichi Abe
Published 2018-04-01

Mutational Profiles Reveal an Aberrant TGF-β-CEA Regulated Pathway in Colon Adenomas.

by Jian Chen, Gottumukkala S Raju, Wilma Jogunoori, Vipin Menon, Avijit Majumdar, Jiun-Sheng Chen, Young Jin Gi, Yun Seong Jeong, Liem Phan, Mitchell Belkin, Shoujun Gu, Suchin Kundra, Nipun A Mistry, Jianping Zhang, Xiaoping Su, Shulin Li, Sue-Hwa Lin, Milind Javle, John S McMurray, Thomas F Rahlfs, Bibhuti Mishra, Jon White, Asif Rashid, Nicole Beauchemin, Brian R Weston, Mehnaz A Shafi, John R Stroehlein, Marta Davila, Rehan Akbani, John N Weinstein, Xifeng Wu, Lopa Mishra
Published 2016-01-01

Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phen...

by Sivareddy Kotla, Aijun Zhang, Masaki Imanishi, Kyung Ae Ko, Steven H. Lin, Young Jin Gi, Margie Moczygemba, Sevinj Isgandarova, Keri L. Schadler, Caroline Chung, Sarah A. Milgrom, Jose Banchs, Syed Wamique Yusuf, Diana N. Amaya, Huifang Guo, Tamlyn N. Thomas, Ying H. Shen, Anita Deswal, Joerg Herrmann, Eugenie S. Kleinerman, Mark L. Entman, John P. Cooke, Giovanni Schifitto, Sanjay B. Maggirwar, Elena McBeath, Anisha A. Gupte, Sunil Krishnan, Zarana S. Patel, Yisang Yoon, Jared K. Burks, Keigi Fujiwara, Paul S. Brookes, Nhat-Tu Le, Dale J. Hamilton, Jun-ichi Abe
Published 2021-11-01